Postdoc in bioinformatics and ai

Your passion for scientific challenges strengthens our research.

The Chien lab (http://www.mpchienlab.org/) is looking for an enthusiastic and motivated bioinformatician to join our collaborative, interdisciplinary environment. If you have a 'can-do' attitude, a goal-oriented mindset, and a passion for (scientific) challenges, you are the right person for us.

Our lab develops technologies that integrate advanced imaging, computational analysis, and single-cell & spatial omics sequencing methods to address key biological questions, particularly in cancer research. Our focus is on investigating the molecular mechanisms underlying rare and aggressive cancer cell subpopulations, as well as (plastic) cancer cell states that contribute to tumor progression, metastasis and therapy resistance.

The candidate will lead several projects applying machine learning to (single-cell) multi-omics analysis for the identification of therapeutic targets (biomarkers or druggable targets). The candidate will also develop and implement AI-driven tools to predict disease prognosis and treatment response from multimodal data. In addition, the role will involve active participation in collaborative projects focused on single-cell (epi)genomics, transcriptomics, and TCR profiling.

The successful candidate will also be part of Oncode Institute (https://www.oncode.nl/), with which Dr. Chien is affiliated.

The Department of Molecular Genetics consists of 13 research groups dedicated to investigating the fundamental mechanistic aspects of tumorigenesis, including the DNA damage response, at molecular, cellular, and physiological levels through multidisciplinary and interdisciplinary research. In collaboration with clinical colleagues at Erasmus MC, the department leverages its findings to develop novel targeted therapies aimed at improving cancer patients' quality of life and promoting a healthy lifespan in an aging population.

• You are in the possession of a PhD in a relevant discipline (computational biology/bioinformatics/statistics/computer science/AI) with a publication record reflecting individual accomplishments.
• You are proficient in Python and/or R; experience with shell scripting (Bash) and AI frameworks.
• You have a strong command of scientific English, both spoken and written.
• You show a can-do attitude, a solution-focused approach, and a goal-oriented mindset.

• You will receive a temporary position for 1 year. Extension is possible. 
• A salary between €3.598,- and up to €5.669,- scale 10. (based on a 36 hour workweek).
• Excellent fringe benefits, such as a 13th month that is already paid out in November and an individual travel expense package. 
• An International Office which aids you in preparing for you arrival and stay. 
• Pension insurance with ABP. We take care of approximately 2/3 of the monthly contribution. 
• Special benefits, such as an incompany physiotherapist and bicycle repairer. And there is also a gym where you can work on your fitness after work. 

For more information you can contact Principal Investigator Miao-Ping Chien: m.p.chien@erasmusmc.nl